2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride basic information

English Name:

2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride

English Synonyms:

1-beta-d-arabinofuranosyl-2,2’-anhydro-cytosinhydrochloride;

hydroxy-6-imino-,monohydrochloride,stereoisomer;nsc-145668;

o-2,2’-cyclocytidinemonohydrochloride;

2,2'-ANHYDRO-(1-BETA-D-ARABINOFURChemicalbookANOSYL)CYTOSINEHYDROCHLORIDE;

2,2'-ANHYDROCYTIDINEHYDROCHLORIDE;

ANCITABINEHYDROCHLORIDE;Ancitabinehydrochloride,2,2′-Anhydro-(1-β-D-arabinofuranosyl)cytosinehydrochloride,Cyclo-C,Cyclocytidine

CAS  :

10212-25-6

Molecular formula:

C9H12ClN3O4

Molecular weight:

261.66

EINECS :

233-515-6

Related categories:

Cell signaling and neurobiology; Other biochemical reagents; Intermediates; Small molecule inhibitors; Active pharmaceutical ingredients. Chemical reagent; Nucleoside; Pharmaceutical intermediates; Nucleosides and their derivatives; Nucleic acid class; Biological chemicals; Nucleic acid; Cell biology; Plant hormones and nucleic acids; Biochemical reagent; Biochemical reagents - plant hormones and nucleic acids; Pharmaceutical bulk drugs; The raw material; Pharmaceutical, pesticide and dye intermediates Chemicalbook; Pharmaceutical and chemical industry; Chemical raw materials; APIintermediates; Biochemistry; Nucleosidesandtheiranalogs;Nucleosides,Nucleotides&RelatedReagents; Pharmaceutical raw materials; General biochemical reagent - sugar

Molecular formula picture:

Product pictures：

2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride properties

Melting point

269-270 °C (dec.)(lit.)

Specific rotation

21.8 º (c=2,water)

Refractive index

-21 ° (C=2, H2O)

Storage conditions

Inert atmosphere,2-8°C

Form

Powder

2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride Purpose and synthesis method

Chemical properties

This product is white needle-like crystal or crystalline powder. Odourless; Soluble in water, slightly soluble in methanol, ethanol, ether, benzene, chloroform almost insoluble; Mp256-262 ℃ (decomposition). Specific rotation -20°--23°(C =2 g/ mL, H2O).

Application

Antineoplastic drugs. The adverse reactions were similar to cytarabine but milder. There is myelosuppression. Leukopenia and thrombocytopenia. Large dosage often appear parotid gland pain, local cold compress can make pain relief. Sometimes can Chemicalbook see salivation, sometimes visible postural hypotension, conjunctival congestion, nasal mucosa swelling, individual patients have headache, rash, occasionally can cause transient pulmonary inflammatory changes. Blood images should be strictly examined during medication.

Application

It is effective for all types of acute leukemia and meningeal leukemia

Application

Make eye drops.

Provider(company)

Language

Xiangyang Meijun Machinery Technology Testing Co., LTD

English