地 址:湖北省襄阳市襄州区光彩台商工业园L1栋3楼
电 话:0710-3311159 13774177198
传 真:0710-3313754
邮 箱:qjuyd@126.com
2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride basic information |
|
English Name: |
2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride |
English Synonyms: |
1-beta-d-arabinofuranosyl-2,2’-anhydro-cytosinhydrochloride; hydroxy-6-imino-,monohydrochloride,stereoisomer;nsc-145668; o-2,2’-cyclocytidinemonohydrochloride; 2,2'-ANHYDRO-(1-BETA-D-ARABINOFURChemicalbookANOSYL)CYTOSINEHYDROCHLORIDE; 2,2'-ANHYDROCYTIDINEHYDROCHLORIDE; ANCITABINEHYDROCHLORIDE;Ancitabinehydrochloride,2,2′-Anhydro-(1-β-D-arabinofuranosyl)cytosinehydrochloride,Cyclo-C,Cyclocytidine |
CAS : |
10212-25-6 |
Molecular formula: |
C9H12ClN3O4 |
Molecular weight: |
261.66 |
EINECS : |
233-515-6 |
Related categories: |
Cell signaling and neurobiology; Other biochemical reagents; Intermediates; Small molecule inhibitors; Active pharmaceutical ingredients. Chemical reagent; Nucleoside; Pharmaceutical intermediates; Nucleosides and their derivatives; Nucleic acid class; Biological chemicals; Nucleic acid; Cell biology; Plant hormones and nucleic acids; Biochemical reagent; Biochemical reagents - plant hormones and nucleic acids; Pharmaceutical bulk drugs; The raw material; Pharmaceutical, pesticide and dye intermediates Chemicalbook; Pharmaceutical and chemical industry; Chemical raw materials; APIintermediates; Biochemistry; Nucleosidesandtheiranalogs;Nucleosides,Nucleotides&RelatedReagents; Pharmaceutical raw materials; General biochemical reagent - sugar
|
Molecular formula picture: |
|
|
|
Product pictures: |
|
|
|
2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride properties |
|
Melting point |
269-270 °C (dec.)(lit.) |
Specific rotation |
21.8 º (c=2,water) |
Refractive index |
-21 ° (C=2, H2O) |
Storage conditions |
Inert atmosphere,2-8°C |
Form |
Powder |
2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride Purpose and synthesis method |
|
Chemical properties |
This product is white needle-like crystal or crystalline powder. Odourless; Soluble in water, slightly soluble in methanol, ethanol, ether, benzene, chloroform almost insoluble; Mp256-262 ℃ (decomposition). Specific rotation -20°--23°(C =2 g/ mL, H2O). |
Application |
Antineoplastic drugs. The adverse reactions were similar to cytarabine but milder. There is myelosuppression. Leukopenia and thrombocytopenia. Large dosage often appear parotid gland pain, local cold compress can make pain relief. Sometimes can Chemicalbook see salivation, sometimes visible postural hypotension, conjunctival congestion, nasal mucosa swelling, individual patients have headache, rash, occasionally can cause transient pulmonary inflammatory changes. Blood images should be strictly examined during medication. |
Application |
It is effective for all types of acute leukemia and meningeal leukemia |
Application |
Make eye drops. |
Provider(company) |
Language |
Xiangyang Meijun Machinery Technology Testing Co., LTD |
English |